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Best Vitamin C: Comparing L-ascorbic acid, Sodium Ascorbyl Phosphate, and Tetrahexyldecyl Ascorbate

Updated: Mar 31


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- L-ascorbic acid is the most common form of ascorbic acid. It acts as a potent antioxidant, can brighten the complexion, reduce hyperpigmentation, and improve skin texture. Its chemical instability is due to its ability to donate electrons and its hydrophilic nature. It is highly susceptible to oxidation in the presence of oxygen, light, and heat. L-ascorbic acid's hydrophilic nature allows it to interact with water-containing structures in the body, but it also contributes to its instability.

- The form of vitamin C known as Sodium Ascorbyl Phosphate (SAP) is more stable and less likely to cause irritation than L-ascorbic acid, and is suitable for use in water-based skincare products. However, it's important to note that the slow conversion process into its active form may limit its effectiveness. Additionally, SAP has a low penetration rate into the skin, which may limit its effects on deeper layers.

- Tetrahexyldecyl ascorbate is a stable form of vitamin C used in skincare for its antioxidant and anti-aging properties. It is effective at reducing the appearance of fine lines and wrinkles, improving skin tone and texture, and brightening the complexion. It is less likely to cause skin irritation and can penetrate deeper layers of the skin. However, it is expensive and limited research is available on its long-term benefits and potential side effects. Some people may not see desired results.



Vitamin C is a potent antioxidant that provides numerous benefits for the skin. As a key ingredient in many skincare products, vitamin C can help to brighten the complexion, reduce hyperpigmentation, improve collagen production, and reduce the appearance of fine lines and wrinkles. It can also help to protect the skin from environmental stressors such as pollution and UV radiation, making it an essential part of any skincare routine. With its powerful antioxidant properties and proven benefits, vitamin C is a must-have ingredient for anyone looking to achieve healthy, glowing skin.




It's important to note that not all vitamin Cs are created equal. There are various forms of vitamin C used in skincare products, and the effectiveness of each can vary. Some forms of vitamin C may be more stable or more potent than others, making it important to carefully consider the specific type of vitamin C used in any skincare product you use. Additionally, the concentration of vitamin C in a product can also impact its effectiveness, with higher concentrations typically providing greater benefits. Therefore, it's important to be informed and select a high-quality vitamin C product that suits your skin type and concerns.



L-ascorbic Acid

This is the most common form of vitamin C used in skincare products. It is a potent antioxidant that can help to brighten the complexion, reduce hyperpigmentation, and improve skin texture. The chemical instability of L-ascorbic acid is due to its ability to donate electrons as well as its hydrophilic nature. It is a potent reducing agent that can donate electrons to other molecules. This ability to donate electrons allows L-ascorbic acid to act as an antioxidant and participate in many biochemical reactions. However, this same property also makes it highly susceptible to oxidation, especially in the presence of oxygen, light, and heat. When L-ascorbic acid undergoes oxidation, it loses its ability to act as an antioxidant and can even become pro-oxidant, causing damage to cells and tissues.

L-ascorbic acid is also hydrophilic, which means it has an affinity for water. This property is due to its chemical structure, which includes hydroxyl (-OH) groups that can form hydrogen bonds with water molecules. Because of its hydrophilicity, L-ascorbic acid is soluble in water and can interact with water-containing structures such as cell cytoplasm and extracellular fluids. This property is important for the transport and distribution of L-ascorbic acid in the body.

L-ascorbic acid's hydrophilic nature also contributes to its instability. Hydrolysis, which is the breakdown of a compound by water, can occur in the presence of water and lead to the degradation of L-ascorbic acid. Additionally, L-ascorbic acid can react with metal ions such as copper and iron, which are present in water and can promote its oxidation.


Sodium Ascorbyl Palmitate

This form of vitamin C is more stable than L-ascorbic acid and is less likely to cause irritation. It is also water-soluble, making it ideal for use in serums and other water-based skincare products.

However, you may want to consider the following before purchasing this form of Vitamin C. Firstly, SAP needs to be converted to ascorbic acid (the active form of vitamin C) by enzymes in the skin before it can provide any benefit, which may limit its effectiveness. Sodium Ascorbyl phosphate (SAP) is a stable derivative of vitamin C that can be converted into ascorbic acid (the active form of vitamin C) through enzymatic hydrolysis.

Enzymatic hydrolysis is a chemical reaction that involves the addition of water to a compound to break it down into its constituent parts. In the case of SAP, an enzyme called phosphatase is required to convert it into ascorbic acid.

Phosphatase is naturally present in the skin and is able to cleave the phosphate group from SAP, which results in the release of ascorbic acid. Once converted to ascorbic acid, it can then act as an antioxidant and perform its other beneficial functions in the skin.

It's worth noting that the conversion of SAP to ascorbic acid is a slow process and may not be as efficient as using other forms of vitamin C that are already in their active form, such as L-ascorbic acid.

Secondly, SAP has a relatively low penetration rate into the skin, which means it may not reach deeper layers where it could have more significant effects. However, SAP's stability and water solubility make it a useful and popular ingredient in skincare products.


Tetrahexyldecyl Ascorbate

Tetrahexyldecyl ascorbate is a form of vitamin C that has gained popularity in the skincare industry for its potent antioxidant and anti-aging properties. One of the key benefits of tetrahexyldecyl ascorbate is its stability. Unlike other forms of vitamin C, it does not degrade easily, allowing it to remain active and effective in skincare products for longer periods of time.

In addition to its stability, tetrahexyldecyl ascorbate is also highly effective at reducing the appearance of fine lines and wrinkles, improving skin tone and texture, and brightening the complexion. This is due to its ability to easily penetrate the skin and reach deeper layers. Furthermore, it is less likely to cause skin irritation than other forms of vitamin C, making it a good choice for those with sensitive skin.

Despite these benefits, there are some downsides to using tetrahexyldecyl ascorbate in skincare. Firstly, it is a relatively expensive ingredient compared to other forms of vitamin C, which can make skincare products containing it more expensive. Additionally, while there is some research supporting its effectiveness, there is still limited data available on its long-term benefits and potential side effects. Finally, while it is generally well-tolerated, some people may not see the desired results from using it.

Ultimately, the best form of vitamin C for the face will depend on your individual skin type and concerns, so it's always a good idea to consult with a skincare professional or dermatologist to determine what product and form of vitamin C will be most beneficial for you.








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